SESN3 Rabbit Polyclonal Antibody (CAB5164)
- SKU:
- CAB5164
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | SESN3 Rabbit Polyclonal Antibody |
SKU: | CAB5164 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-310 of human SESN3 (NP_653266.2). |
Sequence: | MNRG GGSP SAAA NYLL CTNC RKVL RKDK RIRV SQPL TRGP SAFI PEKE VVQA NTVD ERTN FLVE EYST SGRL DNIT QVMS LHTQ YLES FLRS QFYM LRMD GPLP LPYR HYIA IMAA ARHQ CSYL INMH VDEF LKTG GIAE WLNG LEYV PQRL KNLN EINK LLAH RPWL ITKE HIQK LVKT GENN WSLP ELVH AVVL LAHY HALA SFVF GSGI NPER DPEI SNGF RLIS VNNF CVCD LAND NNIE NASL SGSN FGIV DSLS ELEA LMER MKRL QEER EDEE ASQE EMST RFEK EKKE SLFV VSGD TFHS FP |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:200 - 1:2000 |
Synonyms: | SEST3; SESN3 |
Positive Sample: | HeLa,A-549 |
Conjugate: | Unconjugated |
Cellular Localization: | cytoplasm, nucleus |
Calculated MW: | 57kDa |
Observed MW: | 50kDa |
This gene encodes a member of the sestrin family of stress-induced proteins. The encoded protein reduces the levels of intracellular reactive oxygen species induced by activated Ras downstream of RAC-alpha serine/threonine-protein kinase (Akt) and FoxO transcription factor. The protein is required for normal regulation of blood glucose, insulin resistance and plays a role in lipid storage in obesity. Alternative splicing results in multiple transcript variants.
Purification Method: | Affinity purification |
Gene ID: | 143686 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |