The SESN2 Polyclonal Antibody (CAB14220) is a valuable tool for research involving SESN2, a stress-induced protein involved in regulating cellular responses to oxidative stress and DNA damage. This antibody, generated in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding to SESN2 protein, this antibody enables accurate detection and analysis in various cell types, making it ideal for studies in molecular biology and cancer research.SESN2, also known as sestrin 2, is a key player in cellular stress response pathways, helping to maintain cellular homeostasis and protect against oxidative damage.
Its involvement in regulating cell growth, metabolism, and survival makes SESN2 a promising target for investigating diseases such as cancer, neurodegenerative disorders, and metabolic diseases. Understanding the function of SESN2 is essential for developing therapies that target stress-induced pathways and improve cell resilience in various pathological conditions.Overall, the SESN2 Polyclonal Antibody (CAB14220) provides researchers with a reliable tool to investigate the role of SESN2 in cellular stress response mechanisms, offering valuable insights into potential therapeutic strategies for treating diseases associated with oxidative stress and DNA damage.
Product Name:
SESN2 Rabbit Polyclonal Antibody
SKU:
CAB14220
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 211-480 of human SESN2 (NP_113647.1).
This gene encodes a member of the sestrin family of PA26-related proteins. The encoded protein may function in the regulation of cell growth and survival. This protein may be involved in cellular response to different stress conditions.
Purification Method:
Affinity purification
Gene ID:
83667
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using SESN2 antibody (CAB14220) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
