HSP47/SERPINH1 Polyclonal Antibody (CAB13474)
- SKU:
- CAB13474
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Metabolism
Frequently bought together:
Description
Product Name: | HSP47/SERPINH1 Polyclonal Antibody |
SKU: | CAB13474 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 139-418 of human HSP47/HSP47/SERPINH1 (NP_001226.2). |
Sequence: | SVSF ADDF VRSS KQHY NCEH SKIN FRDK RSAL QSIN EWAA QTTD GKLP EVTK DVER TDGA LLVN AMFF KPHW DEKF HHKM VDNR GFMV TRSY TVGV MMMH RTGL YNYY DDEK EKLQ IVEM PLAH KLSS LIIL MPHH VEPL ERLE KLLT KEQL KIWM GKMQ KKAV AISL PKGV VEVT HDLQ KHLA GLGL TEAI DKNK ADLS RMSG KKDL YLAS VFHA TAFE LDTD GNPF DQDI YGRE ELRS PKLF YADH PFIF LVRD TQSG SLLF IGRL VRPK GDKM RDEL |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IF/ICC,1:50 - 1:200 |
Synonyms: | CBP1; CBP2; OI10; gp46; AsTP3; HSP47; PIG14; PPROM; RA-A47; SERPINH2; HSP47/SERPINH1 |
Positive Sample: | NIH/3T3 |
Conjugate: | Unconjugated |
Cellular Localization: | Endoplasmic reticulum lumen. |
Calculated MW: | 46kDa |
Observed MW: | 46kDa |
This gene encodes a member of the serpin superfamily of serine proteinase inhibitors. The encoded protein is localized to the endoplasmic reticulum and plays a role in collagen biosynthesis as a collagen-specific molecular chaperone. Autoantibodies to the encoded protein have been found in patients with rheumatoid arthritis. Expression of this gene may be a marker for cancer, and nucleotide polymorphisms in this gene may be associated with preterm birth caused by preterm premature rupture of membranes. Alternatively spliced transcript variants have been observed for this gene, and a pseudogene of this gene is located on the short arm of chromosome 9.
Purification Method: | Affinity purification |
Gene ID: | 871 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |