Serpinh1 Antibody (PACO29852)
- SKU:
- PACO29852
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- WB
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Frequently bought together:
Description
| Antibody Name: | Serpinh1 Antibody (PACO29852) |
| Antibody SKU: | PACO29852 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:2000 |
| Species Reactivity: | Mouse, Human |
| Immunogen: | Recombinant Mouse Serpin H1 protein (18-417AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western blot All lanes: Serpinh1 antibody at 6µg/ml + Jurkat whole cell lysate Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 47 kDa Observed band size: 47 kDa . |
| Background: | Binds specifically to collagen. Could be involved as a chaperone in the biosynthetic pathway of collagen. |
| Synonyms: | Serpin H1 (47 kDa heat shock protein) (Collagen-binding protein) (Colligin) (Serine protease inhibitor J6), Serpinh1, Cbp1 Hsp47 |
| UniProt Protein Function: | SERPINH1: Binds specifically to collagen. Could be involved as a chaperone in the biosynthetic pathway of collagen. Defects in SERPINH1 are the cause of osteogenesis imperfecta type 10 (OI10). A connective tissue disorder characterized by bone fragility, low bone mass, bowing of limbs due to multiple fractures, short limb dwarfism and blue sclerae. Belongs to the serpin family.Cellular Component: extracellular space; endoplasmic reticulum; cytoplasm; ER-Golgi intermediate compartmentMolecular Function: serine-type endopeptidase inhibitor activity; collagen binding; protein binding; unfolded protein bindingBiological Process: collagen fibril organization; protein maturation; collagen biosynthetic process |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | P19324 |
| NCBI GenInfo Identifier: | 161353504 |
| NCBI Gene ID: | 12406 |
| NCBI Accession: | NP_001104513.1 |
| UniProt Secondary Accession: | P19324,Q5U4D0 |
| UniProt Related Accession: | P19324 |
| Molecular Weight: | |
| NCBI Full Name: | serpin H1 |
| NCBI Synonym Full Names: | serine (or cysteine) peptidase inhibitor, clade H, member 1 |
| NCBI Official Symbol: | Serpinh1Â Â |
| NCBI Official Synonym Symbols: | J6; Cbp1; Cbp2; gp46; Hsp47; BERF-1; Serpinh2Â Â |
| NCBI Protein Information: | serpin H1 |
| UniProt Protein Name: | Serpin H1 |
| UniProt Synonym Protein Names: | 47 kDa heat shock protein; Collagen-binding protein; Colligin; Serine protease inhibitor J6 |
| Protein Family: | |
| UniProt Gene Name: | Serpinh1Â Â |
| UniProt Entry Name: | SERPH_MOUSE |
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