SERPING1 Rabbit Polyclonal Antibody (CAB1717)
- SKU:
- CAB1717
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cardiovascular
Frequently bought together:
Description
Product Name: | SERPING1 Rabbit Polyclonal Antibody |
SKU: | CAB1717 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 201-500 of human SERPING1 (NP_001027466.1). |
Sequence: | KDFT CVHQ ALKG FTTK GVTS VSQI FHSP DLAI RDTF VNAS RTLY SSSP RVLS NNSD ANLE LINT WVAK NTNN KISR LLDS LPSD TRLV LLNA IYLS AKWK TTFD PKKT RMEP FHFK NSVI KVPM MNSK KYPV AHFI DQTL KAKV GQLQ LSHN LSLV ILVP QNLK HRLE DMEQ ALSP SVFK AIME KLEM SKFQ PTLL TLPR IKVT TSQD MLSI MEKL EFFD FSYD LNLC GLTE DPDL QVSA MQHQ TVLE LTET GVEA AAAS AISV ARTL LVFE VQQP FLFV LWDQ QHKF PVFM GRVY DPRA |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IF/ICC,1:50 - 1:200 |
Synonyms: | C1IN; C1NH; HAE1; HAE2; C1INH; SERPING1 |
Positive Sample: | Human plasma |
Conjugate: | Unconjugated |
Cellular Localization: | Secreted. |
Calculated MW: | 55kDa |
Observed MW: | 100kDa |
This gene encodes a highly glycosylated plasma protein involved in the regulation of the complement cascade. Its encoded protein, C1 inhibitor, inhibits activated C1r and C1s of the first complement component and thus regulates complement activation. It is synthesized in the liver, and its deficiency is associated with hereditary angioneurotic oedema (HANE). Alternative splicing results in multiple transcript variants encoding the same isoform.
Purification Method: | Affinity purification |
Gene ID: | 710 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |