SERPING1 Rabbit Polyclonal Antibody (CAB12407)
- SKU:
- CAB12407
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cardiovascular
Frequently bought together:
Description
Product Name: | SERPING1 Rabbit Polyclonal Antibody |
SKU: | CAB12407 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 23-500 of human SERPING1 (NP_000053.2). |
Sequence: | NPNA TSSS SQDP ESLQ DRGE GKVA TTVI SKML FVEP ILEV SSLP TTNS TTNS ATKI TANT TDEP TTQP TTEP TTQP TIQP TQPT TQLP TDSP TQPT TGSF CPGP VTLC SDLE SHST EAVL GDAL VDFS LKLY HAFS AMKK VETN MAFS PFSI ASLL TQVL LGAG ENTK TNLE SILS YPKD FTCV HQAL KGFT TKGV TSVS QIFH SPDL AIRD TFVN ASRT LYSS SPRV LSNN SDAN LELI NTWV AKNT NNKI SRLL DSLP SDTR LVLL NAIY LSAK WKTT FDPK KTRM EPFH FKNS VIKV PMMN SKKY PVAH FIDQ TLKA KVGQ LQLS HNLS LVIL VPQN LKHR LEDM EQAL SPSV FKAI MEKL EMSK FQPT LLTL PRIK VTTS QDML SIME KLEF FDFS YDLN LCGL TEDP DLQV SAMQ HQTV LELT ETGV EAAA ASAI SVAR TLLV FEVQ QPFL FVLW DQQH KFPV FMGR VYDP RA |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IF/ICC,1:50 - 1:200 |
Synonyms: | C1IN; C1NH; HAE1; HAE2; C1INH; SERPING1 |
Positive Sample: | Mouse heart |
Conjugate: | Unconjugated |
Cellular Localization: | Secreted. |
Calculated MW: | 55kDa |
Observed MW: | 60kDa |
This gene encodes a highly glycosylated plasma protein involved in the regulation of the complement cascade. Its encoded protein, C1 inhibitor, inhibits activated C1r and C1s of the first complement component and thus regulates complement activation. It is synthesized in the liver, and its deficiency is associated with hereditary angioneurotic oedema (HANE). Alternative splicing results in multiple transcript variants encoding the same isoform.
Purification Method: | Affinity purification |
Gene ID: | 710 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |