The SerpinF2 Polyclonal Antibody (CAB14043) is a valuable tool for researchers studying SerpinF2, a protein with important roles in coagulation and inflammation regulation. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. By binding to the SerpinF2 protein, this antibody allows for accurate detection and analysis in a variety of cell types, making it an ideal choice for studies in thrombosis, hemostasis, and inflammatory diseases.SerpinF2, also known as alpha-2-antiplasmin, acts as a key inhibitor of plasmin, a protease responsible for fibrinolysis. Dysregulation of SerpinF2 has been associated with various pathological conditions, including thrombosis, hemorrhage, and inflammatory disorders.
By elucidating the functions and regulatory mechanisms of SerpinF2, researchers can gain valuable insights into the molecular pathways underlying these diseases and potentially identify novel therapeutic targets for intervention. Overall, the SerpinF2 Polyclonal Antibody (CAB14043) offers a reliable and versatile tool for investigating the biological roles of SerpinF2 in health and disease, paving the way for advancements in the fields of coagulation, inflammation, and therapeutic development.
Product Name:
SERPINF2 Rabbit Polyclonal Antibody
SKU:
CAB14043
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 302-491 of human SERPINF2 (NP_001159392.1).
This gene encodes a member of the serpin family of serine protease inhibitors. The protein is a major inhibitor of plasmin, which degrades fibrin and various other proteins. Consequently, the proper function of this gene has a major role in regulating the blood clotting pathway. Mutations in this gene result in alpha-2-plasmin inhibitor deficiency, which is characterized by severe hemorrhagic diathesis. Multiple transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
5345
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using SERPINF2 antibody (CAB14043) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
