The SERPINF1 Polyclonal Antibody (CAB1673) is a valuable tool for researchers studying SERPINF1, also known as pigment epithelium-derived factor (PEDF), a multifunctional protein with anti-angiogenic, neurotrophic, and anti-tumorigenic properties. This antibody, raised in rabbits, is highly specific for human samples and has been validated for use in Western blotting applications. It binds specifically to the SERPINF1 protein, allowing for accurate detection and analysis in a variety of cell types. SERPINF1 has been implicated in a wide range of biological processes, including angiogenesis, neuroprotection, and tumorigenesis, making it a key target for research in fields such as cancer biology, neurology, and ophthalmology.
Understanding the role of SERPINF1 in these processes may lead to the development of novel therapeutic strategies for diseases such as cancer and neurodegenerative disorders. Overall, the SERPINF1 Polyclonal Antibody (CAB1673) is a powerful tool for researchers seeking to unravel the complex functions of SERPINF1 and its potential implications in various pathological conditions.
Product Name:
PEDF/SERPINF1 Rabbit Polyclonal Antibody
SKU:
CAB1673
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 141-240 of human PEDF/SERPINF1 (NP_002606.3).
This gene encodes a member of the serpin family that does not display the serine protease inhibitory activity shown by many of the other serpin proteins. The encoded protein is secreted and strongly inhibits angiogenesis. In addition, this protein is a neurotrophic factor involved in neuronal differentiation in retinoblastoma cells. Mutations in this gene were found in individuals with osteogenesis imperfecta, type VI.
Purification Method:
Affinity purification
Gene ID:
5176
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using PEDF/SERPINF1 Rabbit pAb (CAB1673) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
