The SerpinF1 Polyclonal Antibody (CAB11782) is a powerful tool for researchers studying SerpinF1, a member of the serine protease inhibitor family known for its role in regulating inflammation and coagulation pathways. This antibody, produced in rabbits, has been rigorously tested for its specificity in detecting SerpinF1 in human samples, making it an ideal choice for Western blot applications.SerpinF1, also known as pigment epithelium-derived factor (PEDF), is a multifunctional protein with anti-angiogenic and neurotrophic properties. Its diverse functions in various biological processes, including wound healing, neuroprotection, and tumorigenesis, make it a valuable target for investigating diseases such as cancer, diabetes, and neurodegenerative disorders.
By using the SerpinF1 Polyclonal Antibody, researchers can uncover new insights into the mechanisms underlying SerpinF1's biological functions and its potential as a therapeutic target. This antibody enables precise detection and analysis of SerpinF1 expression in different cell types, enhancing our understanding of its roles in health and disease.
Product Name:
PEDF/SERPINF1 Rabbit Polyclonal Antibody
SKU:
CAB11782
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 141-240 of human PEDF/SERPINF1 (NP_002606.3).
This gene encodes a member of the serpin family that does not display the serine protease inhibitory activity shown by many of the other serpin proteins. The encoded protein is secreted and strongly inhibits angiogenesis. In addition, this protein is a neurotrophic factor involved in neuronal differentiation in retinoblastoma cells. Mutations in this gene were found in individuals with osteogenesis imperfecta, type VI.
Purification Method:
Affinity purification
Gene ID:
5176
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using PEDF/SERPINF1 Rabbit pAb (CAB11782) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
