The Serpine2 Polyclonal Antibody (CAB5329) is a valuable tool for researchers studying Serpine2, a protein involved in the regulation of protease activity and blood coagulation. This antibody, raised in rabbits, is highly specific to human samples and has been validated for use in Western blot applications.Serpine2, also known as protease inhibitor, plays a crucial role in controlling the balance between protease activity and blood clotting, making it an important target for studies in vascular biology and hemostasis. Dysregulation of Serpine2 has been linked to various diseases, including thrombosis and cardiovascular disorders, highlighting its potential as a therapeutic target.
By using the Serpine2 Polyclonal Antibody, researchers can detect and analyze the expression of Serpine2 in different cell types and tissues, providing valuable insights into its function and role in disease pathology. This antibody is essential for advancing our understanding of Serpine2 biology and developing targeted strategies for managing related health conditions.
Product Name:
SERPINE2 Rabbit Polyclonal Antibody
SKU:
CAB5329
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 20-398 of human SERPINE2 (NP_006207.1).
This gene encodes a member of the serpin family of proteins, a group of proteins that inhibit serine proteases. Thrombin, urokinase, plasmin and trypsin are among the proteases that this family member can inhibit. This gene is a susceptibility gene for chronic obstructive pulmonary disease and for emphysema. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
5270
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using SERPINE2 antibody (CAB5329) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.