The Serpine2 Polyclonal Antibody (CAB14540) is an essential tool for researchers studying Serpine2, a protein known to regulate various physiological processes. This antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for use in Western blotting applications. By targeting the Serpine2 protein, researchers can accurately detect and analyze its presence in different cell types, making it a valuable asset for investigations in the fields of immunology, cancer research, and beyond.
Serpine2, also known as Glia-derived nexin or protease nexin-1, is involved in a wide range of biological functions, including blood coagulation, fibrinolysis, and tissue remodeling. Its role in regulating these processes makes it a potential target for understanding and potentially treating diseases such as cancer, cardiovascular disorders, and neurological conditions. By unraveling the mechanisms by which Serpine2 operates, researchers can potentially develop novel therapeutic strategies to combat these diseases.
Product Name:
SERPINE2 Rabbit Polyclonal Antibody
SKU:
CAB14540
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 27-398 of human SERPINE2 (NP_006207.1).
This gene encodes a member of the serpin family of proteins, a group of proteins that inhibit serine proteases. Thrombin, urokinase, plasmin and trypsin are among the proteases that this family member can inhibit. This gene is a susceptibility gene for chronic obstructive pulmonary disease and for emphysema. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
5270
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from mouse testis, using SERPINE2 Rabbit pAb (CAB14540) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5s.