null

PAI-1/Serpin E1 Rabbit Polyclonal Antibody (CAB6211)

SKU:
CAB6211
Product Type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology
  • Cell Biology Antibodies 10 Anti-SERPINE1 Antibody CAB6211
  • Cell Biology Antibodies 10 Anti-SERPINE1 Antibody CAB6211
$167 - $503
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:PAI-1/Serpin E1 Rabbit Polyclonal Antibody
SKU:CAB6211
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse,Rat
Immunogen:A synthetic peptide corresponding to a sequence within amino acids 24-199 of human PAI-1/Serpin E1 (NP_000593.1).
Sequence:AQAS KDRN VVFS PYGV ASVL AMLQ LTTG GETQ QQIQ AAMG FKID DKGM APAL RHLY KELM GPWN KDEI STTD AIFV QRDL KLVQ GFMP HFFR LFRS TVKQ VDFS EVER ARFI INDW VKTH TKGM ISNL LGKG AVDQ LTRL VLVN ALYF NGQW KTPF PDSS THRR LFHK SDGS TVSV
Tested Applications:WB IF/ICC ELISA
Recommended Dilution:WB,1:500 - 1:1000 IF/ICC,1:50 - 1:200
Synonyms:PAI; PAI1; PAI-1; PLANH1; PAI-1/Serpin E1
Positive Sample:Rat placenta
Conjugate:Unconjugated
Cellular Localization:Secreted.
Calculated MW:45kDa
Observed MW:48kDa

This gene encodes a member of the serine proteinase inhibitor (serpin) superfamily. This member is the principal inhibitor of tissue plasminogen activator (tPA) and urokinase (uPA), and hence is an inhibitor of fibrinolysis. The protein also functions as a component of innate antiviral immunity. Defects in this gene are the cause of plasminogen activator inhibitor-1 deficiency (PAI-1 deficiency), and high concentrations of the gene product are associated with thrombophilia.

Purification Method:Affinity purification
Gene ID:5054
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Product ImageWestern blot analysis of lysates from Rat placenta, using PAI-1/Serpin E1 Rabbit pAb (CAB6211) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.

Related Products