PAI-1/Serpin E1 Rabbit Polyclonal Antibody (CAB6211)
- SKU:
- CAB6211
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | PAI-1/Serpin E1 Rabbit Polyclonal Antibody |
SKU: | CAB6211 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 24-199 of human PAI-1/Serpin E1 (NP_000593.1). |
Sequence: | AQAS KDRN VVFS PYGV ASVL AMLQ LTTG GETQ QQIQ AAMG FKID DKGM APAL RHLY KELM GPWN KDEI STTD AIFV QRDL KLVQ GFMP HFFR LFRS TVKQ VDFS EVER ARFI INDW VKTH TKGM ISNL LGKG AVDQ LTRL VLVN ALYF NGQW KTPF PDSS THRR LFHK SDGS TVSV |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IF/ICC,1:50 - 1:200 |
Synonyms: | PAI; PAI1; PAI-1; PLANH1; PAI-1/Serpin E1 |
Positive Sample: | Rat placenta |
Conjugate: | Unconjugated |
Cellular Localization: | Secreted. |
Calculated MW: | 45kDa |
Observed MW: | 48kDa |
This gene encodes a member of the serine proteinase inhibitor (serpin) superfamily. This member is the principal inhibitor of tissue plasminogen activator (tPA) and urokinase (uPA), and hence is an inhibitor of fibrinolysis. The protein also functions as a component of innate antiviral immunity. Defects in this gene are the cause of plasminogen activator inhibitor-1 deficiency (PAI-1 deficiency), and high concentrations of the gene product are associated with thrombophilia.
Purification Method: | Affinity purification |
Gene ID: | 5054 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |