The SerpinB4 Polyclonal Antibody (CAB15316) is a potent tool for researchers studying SerpinB4, a serine protease inhibitor involved in a variety of biological processes, including inflammation and immune response regulation. This antibody, produced through immunization of rabbits, exhibits high specificity and sensitivity towards human samples, making it a reliable choice for experiments such as Western blot analysis.SerpinB4, also known as squamous cell carcinoma antigen-1 (SCCA1), is known to play a crucial role in controlling the activity of serine proteases, which are involved in various physiological and pathological processes.
Through its regulatory function, SerpinB4 has been implicated in diseases such as cancer, inflammation, and autoimmune disorders. By targeting SerpinB4, researchers can gain valuable insights into the molecular mechanisms underlying these conditions and potentially identify novel therapeutic targets for intervention. Overall, the SerpinB4 Polyclonal Antibody (CAB15316) provides a valuable tool for investigating the role of SerpinB4 in health and disease, offering new avenues for research in fields such as immunology, oncology, and inflammatory disorders.
Product Name:
SERPINB4 Rabbit Polyclonal Antibody
SKU:
CAB15316
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 300 to the C-terminus of human SERPINB4 (NP_002965.1).
The protein encoded by this gene is a member of the serpin family of serine protease inhibitors. The encoded protein is highly expressed in many tumor cells and can inactivate granzyme M, an enzyme that kills tumor cells. This protein, along with serpin B3, can be processed into smaller fragments that aggregate to form an autoantigen in psoriasis, probably by causing chronic inflammation.
Purification Method:
Affinity purification
Gene ID:
6318
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from Mouse skin, using SERPINB4 Rabbit pAb (CAB15316) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
