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SERPINB4 Rabbit Polyclonal Antibody (CAB15316)

SKU:
CAB15316
Product Type:
Antibody
Reactivity:
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology
€139 - €419
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:SERPINB4 Rabbit Polyclonal Antibody
SKU:CAB15316
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Mouse,Rat
Immunogen:A synthetic peptide corresponding to a sequence within amino acids 300 to the C-terminus of human SERPINB4 (NP_002965.1).
Sequence:RTMG MVNI FNGD ADLS GMTW SHGL SVSK VLHK AFVE VTEE GVEA AAAT AVVV VELS SPST NEEF CCNH PFLF FIRQ NKTN SILF YGRF SSP
Tested Applications:WB ELISA
Recommended Dilution:WB,1:500 - 1:1000
Synonyms:PI11; SCCA1; SCCA2; LEUPIN; SCCA-2; SERPINB4
Positive Sample:Mouse skin
Conjugate:Unconjugated
Cellular Localization:Cytoplasm.
Calculated MW:45kDa
Observed MW:45kDa

The protein encoded by this gene is a member of the serpin family of serine protease inhibitors. The encoded protein is highly expressed in many tumor cells and can inactivate granzyme M, an enzyme that kills tumor cells. This protein, along with serpin B3, can be processed into smaller fragments that aggregate to form an autoantigen in psoriasis, probably by causing chronic inflammation.

Purification Method:Affinity purification
Gene ID:6318
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Product ImageWestern blot analysis of lysates from Mouse skin, using SERPINB4 Rabbit pAb (CAB15316) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.

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