The Anti-SERPINB3 Antibody (CAB0455) is a valuable tool for researchers studying SERPINB3, a member of the serine protease inhibitor family implicated in various cellular processes, including apoptosis and cancer progression. This polyclonal antibody, produced in rabbits, exhibits high specificity for human samples and has been validated for use in Western blot applications. By targeting the SERPINB3 protein, researchers can accurately detect and analyze its expression in different cell types, making it an ideal tool for investigations in cancer biology and cell signaling pathways.
SERPINB3, also known as squamous cell carcinoma antigen 1, is involved in regulating cell survival and proliferation, as well as protecting cells from apoptosis. Its dysregulation has been linked to tumorigenesis and cancer metastasis, making it a promising therapeutic target for cancer treatment. By understanding the function of SERPINB3, researchers can uncover potential strategies for developing targeted therapies against various types of cancer and improving patient outcomes.
Product Name:
SerpinB3 Rabbit Monoclonal Antibody
SKU:
CAB0455
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 301-390 of human SSCA1/SerpinB3 (P29508).
Enables cysteine-type endopeptidase inhibitor activity; protease binding activity; and virus receptor activity. Involved in several processes, including autocrine signaling; paracrine signaling; and regulation of cellular protein metabolic process. Located in cytoplasmic vesicle; extracellular exosome; and nucleus.
Purification Method:
Affinity purification
Gene ID:
6317
Clone Number:
ARC2508
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Immunohistochemistry analysis of paraffin-embedded Mouse skin using SSCA1/SerpinB3 Rabbit mAb (CAB0455) at dilution of 1:100 (40x lens).Perform high pressure antigen retrieval with 10 mM citrate buffer pH 6.0 before commencing with IHC staining protocol.