The SerpinB12 Polyclonal Antibody (PACO12111) is a valuable tool for researchers studying SerpinB12, a member of the serpin superfamily known for its role in regulating protease activity. This antibody, produced in rabbits, demonstrates high reactivity with human samples and has been validated for use in various experimental applications, including Western blotting.SerpinB12 is involved in modulating protease activity, making it a key player in processes such as blood coagulation, inflammation, and tissue remodeling. Its dysregulation has been linked to various diseases, including cancer, cardiovascular disorders, and inflammatory conditions, making it a promising target for therapeutic interventions.
By using the SerpinB12 Polyclonal Antibody, researchers can detect and analyze the expression of SerpinB12 in different cell types and tissues, enabling a better understanding of its function and potential contributions to disease pathogenesis. This antibody is an essential tool for studies in fields such as immunology, oncology, and cardiovascular research, where SerpinB12's role in protease regulation may hold significant implications for disease diagnosis and treatment development.
serpin peptidase inhibitor, clade B (ovalbumin), member 12;SERPINB12;MGC119247;MGC119248;YUKOPIN ;
UniProt Protein Function:
SERPINB12: Inhibits trypsin and plasmin, but not thrombin, coagulation factor Xa, or urokinase-type plasminogen activator. Belongs to the serpin family. Ov-serpin subfamily.Protein type: InhibitorChromosomal Location of Human Ortholog: 18q21.33Cellular Component: cytoplasm; extracellular spaceMolecular Function: serine-type endopeptidase inhibitor activity
