The SerpinB1 Polyclonal Antibody (CAB6257) is a valuable tool for researchers studying SerpinB1, a serine protease inhibitor involved in regulating various physiological processes. This antibody, generated in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. By binding to the SerpinB1 protein, this antibody allows for precise detection and analysis in a variety of cell types, making it an essential reagent for studies in immunology, cancer research, and beyond.SerpinB1 is known for its ability to modulate proteolytic activity, playing a crucial role in processes such as blood coagulation, inflammation, and immune response regulation.
Dysregulation of SerpinB1 has been linked to various diseases, making it a promising target for therapeutic interventions. By further understanding the function of SerpinB1, researchers can gain insights into potential treatments for conditions such as cancer, thrombosis, and inflammatory disorders.In conclusion, the SerpinB1 Polyclonal Antibody (CAB6257) offers researchers a powerful tool for investigating the role of SerpinB1 in physiological and pathological processes. Its high specificity and validation for use in Western blot applications make it a reliable choice for studies seeking to unravel the complexity of SerpinB1 function.
Product Name:
SERPINB1 Rabbit Polyclonal Antibody
SKU:
CAB6257
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 100-379 of human SERPINB1 (NP_109591.1).
The protein encoded by this gene is a member of the serpin family of proteinase inhibitors. Members of this family maintain homeostasis by neutralizing overexpressed proteinase activity through their function as suicide substrates. This protein inhibits the neutrophil-derived proteinases neutrophil elastase, cathepsin G, and proteinase-3 and thus protects tissues from damage at inflammatory sites. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
1992
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of various lysates using SERPINB1 Rabbit pAb (CAB6257) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
