The Kallistatin Polyclonal Antibody (CAB7320) is a valuable tool for researchers studying kallistatin, a protein with diverse functions in cardiovascular health, inflammation, and cancer. This antibody, generated in rabbits, demonstrates high specificity and sensitivity in detecting kallistatin in human samples, particularly in Western blot applications. By binding to the kallistatin protein, researchers can accurately assess its levels and activity in various cell types, making it an essential tool for investigations in cardiovascular biology and cancer research.
Kallistatin, known for its anti-inflammatory and anti-angiogenic properties, has emerged as a potential therapeutic target for cardiovascular diseases, cancer, and other inflammatory conditions. Its role in regulating blood pressure, angiogenesis, and inflammation highlights its potential as a biomarker and therapeutic agent. Research using the Kallistatin Polyclonal Antibody can provide insights into the mechanisms by which kallistatin exerts its protective effects and may lead to the development of novel therapies targeting this protein.
Product Name:
SERPINA4 Rabbit Polyclonal Antibody
SKU:
CAB7320
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 178-427 of human Kallistatin (SERPINA4) (NP_006206.2).
Predicted to enable serine-type endopeptidase inhibitor activity. Predicted to be involved in negative regulation of endopeptidase activity. Located in extracellular exosome. Biomarker of diabetic retinopathy.
Purification Method:
Affinity purification
Gene ID:
5267
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of Human plasma, using Kallistatin (SERPINA4) Rabbit pAb antibody (CAB7320) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
