Serpina3n Antibody (PACO38386)
- SKU:
- PACO38386
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
Serpina3n Antibody (PACO38386)
The Serpina3N Polyclonal Antibody (PAC038386) is a valuable tool for researchers studying Serpina3N, a member of the serine protease inhibitor superfamily known for its role in inflammation and immune regulation. This antibody, generated in rabbits, exhibits high reactivity with human samples and is validated for use in a variety of applications, including Western blotting.Serpina3N, also known as alpha-1-antichymotrypsin, is involved in modulating inflammatory responses and immune system activity. Its dysregulation has been implicated in various diseases, including cancer and neurodegenerative disorders, making it a promising target for therapeutic interventions.
By detecting and analyzing the presence of Serpina3N in different cell types, researchers can gain crucial insights into its biological functions and potential implications in disease pathology.The Serpina3N Polyclonal Antibody is an essential tool for investigating the role of Serpina3N in various physiological and pathological processes, opening up new avenues for research in immunology, oncology, and neurology. Its specificity and reliability make it a valuable asset for scientists seeking to deepen their understanding of the intricate mechanisms underlying immune regulation and inflammation.
| Antibody Name: | Serpina3n Antibody (PACO38386) |
| Antibody SKU: | PACO38386 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA |
| Recommended Dilutions: | |
| Species Reactivity: | Mouse |
| Immunogen: | Recombinant Mouse Serine protease inhibitor A3N protein (21-418AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Background: | blood microparticle, extracellular exosome, extracellular region, extracellular space, serine-type endopeptidase inhibitor activity, negative regulation of endopeptidase activity, response to cytokine, response to peptide hormone |
| Synonyms: | Serine protease inhibitor A3N (Serpin A3N), Serpina3n, Spi2 |
| UniProt Protein Function: | SERPINA3: Although its physiological function is unclear, it can inhibit neutrophil cathepsin G and mast cell chymase, both of which can convert angiotensin-1 to the active angiotensin-2. Belongs to the serpin family. 3 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Secreted; Secreted, signal peptide Chromosomal Location of Human Ortholog: 12|12 E Cellular Component: extracellular region; extracellular space Molecular Function:serine-type endopeptidase inhibitor activity Biological Process: response to cytokine stimulus; response to peptide hormone stimulus |
| UniProt Code: | Q91WP6 |
| NCBI GenInfo Identifier: | 68053311 |
| NCBI Gene ID: | 20716 |
| NCBI Accession: | Q91WP6.1 |
| UniProt Secondary Accession: | Q91WP6,Q62258, |
| UniProt Related Accession: | Q91WP6 |
| Molecular Weight: | 46.76kD |
| NCBI Full Name: | Serine protease inhibitor A3N |
| NCBI Synonym Full Names: | serine (or cysteine) peptidase inhibitor, clade A, member 3N |
| NCBI Official Symbol: | Serpina3n  |
| NCBI Official Synonym Symbols: | Spi2-2; Spi2.2; Spi2/eb.4Â Â |
| NCBI Protein Information: | serine protease inhibitor A3N |
| UniProt Protein Name: | Serine protease inhibitor A3N |
| Protein Family: | Serine protease inhibitor |
| UniProt Gene Name: | Serpina3n  |
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