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Alpha-1 Antichymotrypsin (SERPINA3) Rabbit Polyclonal Antibody (CAB1021)

SKU:
CAB1021
Product Type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Immunology
  • Immunology Antibodies 1 Anti-SERPINA3 Antibody CAB1021
  • Immunology Antibodies 1 Anti-SERPINA3 Antibody CAB1021
  • Immunology Antibodies 1 Anti-SERPINA3 Antibody CAB1021
  • Immunology Antibodies 1 Anti-SERPINA3 Antibody CAB1021
€139 - €419
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Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:Alpha-1 Antichymotrypsin (SERPINA3) Rabbit Polyclonal Antibody
SKU:CAB1021
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 24-423 of human Alpha-1 Antichymotrypsin (Alpha-1 Antichymotrypsin (SERPINA3)) (NP_001076.2).
Sequence:HPNS PLDE ENLT QENQ DRGT HVDL GLAS ANVD FAFS LYKQ LVLK APDK NVIF SPLS ISTA LAFL SLGA HNTT LTEI LKGL KFNL TETS EAEI HQSF QHLL RTLN QSSD ELQL SMGN AMFV KEQL SLLD RFTE DAKR LYGS EAFA TDFQ DSAA AKKL INDY VKNG TRGK ITDL IKDL DSQT MMVL VNYI FFKA KWEM PFDP QDTH QSRF YLSK KKWV MVPM MSLH HLTI PYFR DEEL SCTV VELK YTGN ASAL FILP DQDK MEEV EAML LPET LKRW RDSL EFRE IGEL YLPK FSIS RDYN LNDI LLQL GIEE AFTS KADL SGIT GARN LAVS QVVH KAVL DVFE EGTE ASAA TAVK ITLL SALV ETRT IVRF NRPF LMII VPTD TQNI FFMS KVTN PKQA
Tested Applications:WB IHC-P ELISA
Recommended Dilution:WB,1:100 - 1:500 IHC-P,1:50 - 1:200
Synonyms:ACT; AACT; GIG24; GIG25; Alpha-1 Antichymotrypsin (SERPINA3)
Positive Sample:MCF7,U2OS
Conjugate:Unconjugated
Cellular Localization:Secreted.
Calculated MW:48kDa
Observed MW:50-76kDa

The protein encoded by this gene is a member of the serpin family of proteins, a group of proteins that inhibit serine proteases. This gene is one in a cluster of serpin genes located on the q arm of chromosome 14. Polymorphisms in this protein appear to be tissue specific and influence protease targeting. Variations in this protein's sequence have been implicated in Alzheimer's disease, and deficiency of this protein has been associated with liver disease. Mutations have been identified in patients with Parkinson disease and chronic obstructive pulmonary disease.

Purification Method:Affinity purification
Gene ID:12
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Product ImageWestern blot analysis of various lysates, using Alpha-1 Antichymotrypsin (SERPINA3) Rabbit pAb (CAB1021) at 1:400 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.

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