The SERPINA10 Polyclonal Antibody (CAB4717) is a valuable tool for researchers studying SERPINA10, a protein associated with the regulation of blood coagulation. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding specifically to the SERPINA10 protein, this antibody allows for accurate detection and analysis in a variety of cell types, making it ideal for research in hemostasis and thrombosis.SERPINA10, also known as protein Z-dependent protease inhibitor, plays a crucial role in the anticoagulant pathway by inhibiting the activity of coagulation factor Xa.
Dysfunction of SERPINA10 has been linked to an increased risk of thrombotic events, making it a promising target for studies on blood clotting disorders and cardiovascular diseases. By investigating the function of SERPINA10, researchers can gain valuable insights into the mechanisms underlying coagulation and develop potential therapeutic interventions for related pathologies.
Product Name:
SERPINA10 Rabbit Polyclonal Antibody
SKU:
CAB4717
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 165-444 of human SERPINA10 (NP_001094077.1).
The protein encoded by this gene belongs to the serpin family. It is predominantly expressed in the liver and secreted in plasma. It inhibits the activity of coagulation factors Xa and XIa in the presence of protein Z, calcium and phospholipid. Mutations in this gene are associated with venous thrombosis. Alternatively spliced transcript variants have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
51156
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of HepG2 cells, using SERPINA10 antibody (CAB4717) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 120s.
