Alpha-1 Antitrypsin (SERPINA1) Rabbit Monoclonal Antibody (CAB4966)
- SKU:
- CAB4966
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Immunology
Frequently bought together:
Description
Product Name: | Alpha-1 Antitrypsin (SERPINA1) Rabbit Monoclonal Antibody |
SKU: | CAB4966 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-418 of human Alpha-1 Antitrypsin (SERPINA1) (NP_000286.3). |
Sequence: | MPSS VSWG ILLL AGLC CLVP VSLA EDPQ GDAA QKTD TSHH DQDH PTFN KITP NLAE FAFS LYRQ LAHQ SNST NIFF SPVS IATA FAML SLGT KADT HDEI LEGL NFNL TEIP EAQI HEGF QELL RTLN QPDS QLQL TTGN GLFL SEGL KLVD KFLE DVKK LYHS EAFT VNFG DTEE AKKQ INDY VEKG TQGK IVDL VKEL DRDT VFAL VNYI FFKG KWER PFEV KDTE EEDF HVDQ VTTV KVPM MKRL GMFN IQHC KKLS SWVL LMKY LGNA TAIF FLPD EGKL QHLE NELT HDII TKFL ENED RRSA SLHL PKLS ITGT YDLK SVLG QLGI TKVF SNGA DLSG VTEE APLK LSKA VHKA VLTI DEKG TEAA GAMF LEAI PMSI PPEV KFNK PFVF LMIE QNTK SPLF MGKV VNPT QK |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:1000 - 1:5000 |
Synonyms: | PI; A1A; AAT; PI1; A1AT; nNIF; PRO2275; alpha1AT; Alpha-1 Antitrypsin (SERPINA1) |
Positive Sample: | Mouse lung,Mouse liver,Rat lung |
Conjugate: | Unconjugated |
Cellular Localization: | Endoplasmic reticulum, Secreted, extracellular matrix, extracellular space |
Calculated MW: | 47kDa |
Observed MW: | 45kDa |
The protein encoded by this gene is a serine protease inhibitor belonging to the serpin superfamily whose targets include elastase, plasmin, thrombin, trypsin, chymotrypsin, and plasminogen activator. This protein is produced in the liver, the bone marrow, by lymphocytic and monocytic cells in lymphoid tissue, and by the Paneth cells of the gut. Defects in this gene are associated with chronic obstructive pulmonary disease, emphysema, and chronic liver disease. Several transcript variants encoding the same protein have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 5265 |
Clone Number: | ARC1212 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |