null

Alpha-1 Antitrypsin (SERPINA1) Rabbit Polyclonal Antibody (CAB12481)

SKU:
CAB12481
Product Type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Immunology
  • Immunology Antibodies 1 Anti-SERPINA1 Antibody CAB12481
  • Immunology Antibodies 1 Anti-SERPINA1 Antibody CAB12481
  • Immunology Antibodies 1 Anti-SERPINA1 Antibody CAB12481
  • Immunology Antibodies 1 Anti-SERPINA1 Antibody CAB12481
€139 - €419
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:Alpha-1 Antitrypsin (SERPINA1) Rabbit Polyclonal Antibody
SKU:CAB12481
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse,Rat
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 25-315 of human Alpha-1 Antitrypsin (Alpha-1 Antitrypsin (SERPINA1)) (NP_000286.3).
Sequence:EDPQ GDAA QKTD TSHH DQDH PTFN KITP NLAE FAFS LYRQ LAHQ SNST NIFF SPVS IATA FAML SLGT KADT HDEI LEGL NFNL TEIP EAQI HEGF QELL RTLN QPDS QLQL TTGN GLFL SEGL KLVD KFLE DVKK LYHS EAFT VNFG DTEE AKKQ INDY VEKG TQGK IVDL VKEL DRDT VFAL VNYI FFKG KWER PFEV KDTE EEDF HVDQ VTTV KVPM MKRL GMFN IQHC KKLS SWVL LMKY LGNA TAIF FLPD EGKL QHLE NELT HDII TKFL ENED RRSA SLHL PKL
Tested Applications:WB IF/ICC ELISA
Recommended Dilution:WB,1:500 - 1:2000 IF/ICC,1:50 - 1:200
Synonyms:PI; A1A; AAT; PI1; A1AT; nNIF; PRO2275; alpha1AT; Alpha-1 Antitrypsin (SERPINA1)
Positive Sample:SW480,HT-29,Mouse lung
Conjugate:Unconjugated
Cellular Localization:Endoplasmic reticulum, Secreted, extracellular matrix, extracellular space.
Calculated MW:47kDa
Observed MW:45kDa,50kDa

The protein encoded by this gene is a serine protease inhibitor belonging to the serpin superfamily whose targets include elastase, plasmin, thrombin, trypsin, chymotrypsin, and plasminogen activator. This protein is produced in the liver, the bone marrow, by lymphocytic and monocytic cells in lymphoid tissue, and by the Paneth cells of the gut. Defects in this gene are associated with chronic obstructive pulmonary disease, emphysema, and chronic liver disease. Several transcript variants encoding the same protein have been found for this gene.

Purification Method:Affinity purification
Gene ID:5265
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Product ImageWestern blot analysis of extracts of various cell lines, using Alpha-1 Antitrypsin (Alpha-1 Antitrypsin (SERPINA1)) antibody (CAB12481) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.

Related Products