The Serpin I2 Polyclonal Antibody (CAB11732) is a valuable tool for research involving Serpin I2, a serine protease inhibitor involved in regulating various physiological processes. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By targeting the Serpin I2 protein, this antibody enables precise detection and analysis in a variety of cell types, making it an essential component for studies in areas such as immunology and cancer research.Serpin I2, also known as protease inhibitor 6, plays a crucial role in controlling protease activity, which is essential for maintaining proper cellular function and preventing damage caused by uncontrolled proteolytic activity.
Its involvement in pathways related to inflammation and tissue remodeling highlights its significance in various disease processes, including cancer and inflammatory disorders. By delving into the mechanisms of action of Serpin I2, researchers can gain insight into potential therapeutic targets for conditions where protease dysregulation plays a prominent role.
Product Name:
SERPINI2 Rabbit Polyclonal Antibody
SKU:
CAB11732
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 56-405 of human SERPINI2 (NP_006208.1).
The gene encodes a member of a family of proteins that acts as inhibitors of serine proteases. These proteins function in the regulation of a variety of physiological processes, including coagulation, fibrinolysis, development, malignancy, and inflammation. Expression of the encoded protein may be downregulated during pancreatic carcinogenesis. Alternative splicing results in multiple transcript variants for this gene.
Purification Method:
Affinity purification
Gene ID:
5276
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using SERPINI2 Rabbit pAb (CAB11732) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
