The Serpin B9 Polyclonal Antibody (CAB6393) is a valuable tool for researchers studying Serpin B9, a member of the serine protease inhibitor family known for its role in regulating protease activity. This antibody is produced in rabbits and exhibits high reactivity with human samples, making it suitable for use in various experimental applications such as Western blotting.Serpin B9 is involved in inhibiting the activity of specific proteases, thereby playing a crucial role in controlling various physiological processes such as blood coagulation and inflammation. Dysregulation of Serpin B9 has been linked to several diseases, including cancer and chronic inflammatory conditions, making it a promising target for therapeutic intervention.
By using the Serpin B9 Polyclonal Antibody, researchers can detect and analyze the expression of Serpin B9 in different cell types, providing valuable insights into its function and potential implications in disease pathology. This antibody is a valuable tool for investigators in the fields of biochemistry, molecular biology, and pharmacology who are interested in unraveling the intricate roles of Serpin B9 in health and disease.
Product Name:
SERPINB9 Rabbit Polyclonal Antibody
SKU:
CAB6393
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 170-308 of human SERPINB9 (NP_004146.1).
This gene encodes a member of the serine protease inhibitor family which are also known as serpins. The encoded protein belongs to a subfamily of intracellular serpins. This protein inhibits the activity of the effector molecule granzyme B. Overexpression of this protein may prevent cytotoxic T-lymphocytes from eliminating certain tumor cells. A pseudogene of this gene is found on chromosome 6.
Purification Method:
Affinity purification
Gene ID:
5272
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using SERPINB9 antibody (CAB6393) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
