SERPINB6 Rabbit Polyclonal Antibody (CAB9944)
- SKU:
- CAB9944
- Product Type:
- Antibody
- Applications:
- WB
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | SERPINB6 Rabbit Polyclonal Antibody |
SKU: | CAB9944 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 180-300 of human SERPINB6 (NP_004559.4). |
Sequence: | ENTE ERLF KVSK NEEK PVQM MFKQ STFK KTYI GEIF TQIL VLPY VGKE LNMI IMLP DETT DLRT VEKE LTYE KFVE WTRL DMMD EEEV EVSL PRFK LEES YDME SVLR NLGM TDAF ELGK A |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 |
Synonyms: | CAP; PI6; PTI; PI-6; SPI3; DFNB91; MSTP057; SERPINB6 |
Positive Sample: | HeLa,Mouse liver,Rat liver |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm. |
Calculated MW: | 43kDa |
Observed MW: | 42kDa |
The protein encoded by this gene is a member of the serpin (serine proteinase inhibitor) superfamily, and ovalbumin(ov)-serpin subfamily. It was originally discovered as a placental thrombin inhibitor. The mouse homolog was found to be expressed in the hair cells of the inner ear. Mutations in this gene are associated with nonsyndromic progressive hearing loss, suggesting that this serpin plays an important role in the inner ear in the protection against leakage of lysosomal content during stress, and that loss of this protection results in cell death and sensorineural hearing loss. Alternatively spliced transcript variants have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 5269 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |