The Serpin B5 Polyclonal Antibody (CAB1179) is a powerful tool for researchers studying Serpin B5, a member of the serine protease inhibitor superfamily known for its role in regulating protease activity and modulating immune response. This antibody, developed in rabbits, demonstrates high reactivity with human samples and has been validated for use in Western blot applications.Serpin B5, also known as Maspin, has been implicated in various physiological and pathological processes, including cancer progression, inflammation, and tissue remodeling.
By specifically targeting Serpin B5, researchers can gain valuable insights into its functions and potential therapeutic applications in cancer and inflammatory diseases.With its ability to bind to Serpin B5 protein and facilitate its detection in different cell types, the Serpin B5 Polyclonal Antibody is a valuable tool for investigations in oncology, immunology, and beyond. By studying the role of Serpin B5 in disease mechanisms, researchers can uncover new therapeutic targets and strategies for intervention.
Product Name:
SERPINB5 Rabbit Polyclonal Antibody
SKU:
CAB1179
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 21-189 of human SERPINB5 (NP_002630.2).
Predicted to enable serine-type endopeptidase inhibitor activity. Predicted to be involved in negative regulation of endopeptidase activity. Predicted to act upstream of or within several processes, including extracellular matrix organization; prostate gland morphogenesis; and regulation of epithelial cell proliferation. Located in cytoplasm. Biomarker of hepatocellular carcinoma.
Purification Method:
Affinity purification
Gene ID:
5268
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of lysates from wild type(WT) and SERPINB5 knockout (KO) HeLa(KO) cells, using [KO Validated] SERPINB5 Rabbit pAb (CAB1179) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5s.
