The Serpin B3 Polyclonal Antibody (CAB5418) is a valuable tool for researchers studying Serpin B3, a protein involved in various cellular processes, including apoptosis and inflammation. This antibody, generated in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. By specifically targeting the Serpin B3 protein, this antibody enables accurate detection and analysis in a variety of cell types, making it ideal for research in fields such as immunology and cancer biology.
Serpin B3, also known as squamous cell carcinoma antigen 1, has been implicated in cancer progression, as well as in inflammatory responses and cell survival pathways. Its diverse roles in cellular function make it a key target for investigation in diseases such as cancer, inflammatory disorders, and metabolic conditions. Understanding the molecular mechanisms involving Serpin B3 is essential for the development of potential therapeutics targeting these pathways.
Product Name:
SERPINB3 Rabbit Polyclonal Antibody
SKU:
CAB5418
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 2-390 of human SSCA1/SerpinB3 (NP_008850.1).
Enables cysteine-type endopeptidase inhibitor activity; protease binding activity; and virus receptor activity. Involved in several processes, including autocrine signaling; paracrine signaling; and regulation of cellular protein metabolic process. Located in cytoplasmic vesicle; extracellular exosome; and nucleus.
Purification Method:
Affinity purification
Gene ID:
6317
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of lysates from wild type (WT) and 293T cells transfected with SSCA1/SerpinB3 using SSCA1/SerpinB3 Rabbit pAb (CAB5418) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
