The Serine Racemase Polyclonal Antibody (CAB9325) is a valuable tool for researchers studying serine racemase, an enzyme involved in the biosynthesis of D-serine, an important co-agonist of the N-methyl-D-aspartate (NMDA) receptor. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications.Serine racemase plays a crucial role in regulating neurotransmission and synaptic plasticity, making it a key target for studying neurological disorders such as schizophrenia, Alzheimer's disease, and amyotrophic lateral sclerosis (ALS).
By detecting and analyzing the expression of serine racemase in various cell types, researchers can gain insights into the role of D-serine in excitatory neurotransmission and its implications for neurological function.The Serine Racemase Polyclonal Antibody is a valuable tool for scientists conducting research in neurobiology, pharmacology, and drug discovery. By understanding the function of serine racemase and its impact on neurodegenerative diseases, researchers can potentially develop novel therapeutic interventions targeting the NMDA receptor system.
Product Name:
SRR Rabbit Polyclonal Antibody
SKU:
CAB9325
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-340 of human SRR (NP_068766.1).
Enables several functions, including L-serine ammonia-lyase activity; PDZ domain binding activity; and anion binding activity. Involved in pyruvate biosynthetic process; response to lipopolysaccharide; and serine family amino acid metabolic process. Located in cytoplasm and neuronal cell body.
Purification Method:
Affinity purification
Gene ID:
63826
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using SRR antibody (CAB9325) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
