The SERINC3 Polyclonal Antibody (PAC023529) offered by AssayGenie is a vital tool for researchers studying SERINC3, a protein involved in lipid metabolism and virus-host interactions. This antibody, developed through rabbit immunization, demonstrates high specificity for human samples and is optimized for Western blot applications. By targeting the SERINC3 protein, this antibody allows for precise detection and analysis in various cell types, making it an essential resource for studies in virology and lipid biology.SERINC3, a member of the serine incorporator (SERINC) family, is known for its role in regulating lipid composition in membranes, which impacts crucial cellular functions such as viral entry and host immunity.
Research on SERINC3 is particularly relevant to understanding how viruses manipulate host cells during infection and how lipid metabolism influences viral pathogenesis. The SERINC3 Polyclonal Antibody enables researchers to investigate the intricate mechanisms underlying these processes, providing insights that could lead to the development of novel antiviral strategies and lipid-targeted therapies.
Antibody Name:
SERINC3 Antibody (PACO23529)
Antibody SKU:
PACO23529
Size:
100ul
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:2000-1:10000, IHC:1:50-1:100
Species Reactivity:
Human, Mouse, Rat
Immunogen:
Synthetic peptide corresponding to a region derived from internal residues of human serine incorporator 3
Form:
Liquid
Storage Buffer:
Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
Purification Method:
Antigen Affinity Purified
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Immunohistochemical analysis of paraffin-embedded Human breast cancer tissue using at dilution 1/40.
Immunohistochemical analysis of paraffin-embedded Human colon cancer tissue using at dilution 1/40.
Background:
TDE1, tumor differentially expressed protein 1, is a multi-pass membrane protein also known as serine incorporator 3. Also found on the membranes of the Golgi apparatus within cells, TDE1 is highly expressed in neuronal populations but is also found in thymus, kidney, liver and testis. Expression levels of TDE1 in tumors can be as much as tenfold the amount found in normal tissue of the same type. This increased expression implicates TDE1 as being involved in the cellular transformation from normal to malignant tissue.
Synonyms:
TDE; TDE1; AIGP1; TMS-1; DIFF33; SBBI99
UniProt Protein Function:
SERINC3: May be involved in cellular transformation. Belongs to the TDE1 family.
UniProt Protein Details:
Protein type:Cell surface; Membrane protein, multi-pass; Membrane protein, integral
