The Serinc2 Antibody (PAC020438) is a novel tool for researchers studying Serinc2, a protein involved in lipid metabolism and viral replication. This polyclonal antibody, produced using high-quality rabbit serum, displays strong reactivity with human samples and is suitable for use in Western blotting experiments. By targeting the Serinc2 protein, this antibody enables accurate detection and analysis in a variety of cell types, making it an excellent choice for investigations in virology and lipid biology.
Serinc2, a transmembrane protein known to influence lipid composition in cell membranes, has been linked to viral entry and replication in recent studies. Understanding the role of Serinc2 is key to uncovering its potential as a therapeutic target for viral infections, including HIV and influenza. The versatility of the Serinc2 Antibody allows for detailed exploration of its functions, shedding light on its involvement in lipid metabolism and viral pathogenesis.
The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using PACO20438(SERINC2 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: x200).
Gel: 8%SDS-PAGE, Lysate: 40 µg, Lane 1-6: K562 cells, NIH/3T3 cells, Jurkat cells, 293T cells, 231 cells, hepg2 cells, Primary antibody: PACO20438(SERINC2 Antibody) at dilution 1/200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute.
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using PACO20438(SERINC2 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: x200).
Background:
SERINC2 involved in phosphatidylserine metabolic process, and positive regulation of transferase activity.
Synonyms:
serine incorporator 2
UniProt Protein Function:
SERINC2: Belongs to the TDE1 family. 3 isoforms of the human protein are produced by alternative splicing.Protein type: Membrane protein, multi-pass; Membrane protein, integralChromosomal Location of Human Ortholog: 1p35.1Cellular Component: integral to membraneMolecular Function: L-serine transmembrane transporter activity