The SERGEF Polyclonal Antibody (PAC022587) is a crucial tool for researchers studying the protein SERGEF, an essential regulator of intracellular signaling pathways. This antibody, developed using advanced techniques and raised in rabbits, offers high specificity and sensitivity in detecting SERGEF in various samples. It has been validated for use in Western blot applications, allowing for precise analysis of SERGEF expression levels in different cell types.SERGEF is known for its role in promoting cellular signaling cascades that regulate processes such as cell growth, proliferation, and survival. Dysregulation of SERGEF expression has been linked to various diseases, including cancer and neurological disorders.
By using the SERGEF Polyclonal Antibody, researchers can gain valuable insights into the function of SERGEF and its potential involvement in these pathological conditions.This antibody is a valuable tool for studies in cell biology, molecular biology, and drug development, providing researchers with the means to explore the intricate mechanisms underlying cellular signaling pathways. With its high specificity and reliability, the SERGEF Polyclonal Antibody is an indispensable resource for advancing our understanding of the molecular pathways controlled by SERGEF.
Antibody Name:
SERGEF Antibody (PACO22587)
Antibody SKU:
PACO22587
Size:
100ul
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
ELISA:1:2000-1:10000, WB:1:500-1:3000
Species Reactivity:
Human
Immunogen:
Synthesized peptide derived from internal of human SERGEF.
Form:
Liquid
Storage Buffer:
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Western blot analysis of extracts from NIH/3T3 cells, using SERGEF antibody.
Background:
Probable guanine nucleotide exchange factor (GEF), which may be involved in the secretion process.
SERGEF: Probable guanine nucleotide exchange factor (GEF), which may be involved in the secretion process. 2 isoforms of the human protein are produced by alternative splicing.Protein type: GEFs; GEFs, RasChromosomal Location of Human Ortholog: 11p14.3Cellular Component: intermediate filament cytoskeleton; cytoplasm; nucleolus; nucleusMolecular Function: protein binding; Ran guanyl-nucleotide exchange factor activityBiological Process: negative regulation of protein secretion; signal transduction
