The Septin 9 Polyclonal Antibody (CAB8657) is a crucial tool for research involving Septin 9, a protein involved in cell division and cellular structure. This antibody is raised in rabbits and has high reactivity with human samples, making it ideal for use in Western blot applications. By binding specifically to the Septin 9 protein, this antibody allows for the detection and analysis of Septin 9 in a variety of cell types.Septin 9 plays an important role in cell division and has been linked to various diseases, including cancer.
Research on Septin 9 can provide valuable insights into the mechanisms underlying these diseases and may offer new potential targets for therapeutic interventions. By studying the activity of Septin 9, researchers can further our understanding of cellular processes and potentially develop new treatments for cancer and other related conditions.
Product Name:
Septin 9 Rabbit Polyclonal Antibody
SKU:
CAB8657
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-110 of human Septin 9 (NP_001106964.1).
This gene is a member of the septin family involved in cytokinesis and cell cycle control. This gene is a candidate for the ovarian tumor suppressor gene. Mutations in this gene cause hereditary neuralgic amyotrophy, also known as neuritis with brachial predilection. A chromosomal translocation involving this gene on chromosome 17 and the MLL gene on chromosome 11 results in acute myelomonocytic leukemia. Multiple alternatively spliced transcript variants encoding different isoforms have been described.
Purification Method:
Affinity purification
Gene ID:
10801
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using Septin 9 antibody (CAB8657) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5s.
