The Septin 8 Monoclonal Antibody is a crucial tool for researchers studying the role of Septin 8, a member of the septin family of GTP-binding proteins, in various cellular processes. This antibody, generated from mouse hybridoma cells, is highly specific to human Septin 8 and has been validated for use in immunocytochemistry, immunoprecipitation, and other research applications.Septins are known to play important roles in cell division, cytoskeletal organization, and membrane dynamics, making them key players in cell biology and disease development. Septin 8, in particular, has been implicated in cancer progression, neuronal development, and membrane trafficking.
By utilizing the Septin 8 Monoclonal Antibody, researchers can gain valuable insights into the function and localization of Septin 8 in various cell types and disease contexts.With its high specificity and versatility in applications, the Septin 8 Monoclonal Antibody is a valuable tool for researchers interested in unraveling the complex mechanisms underlying cellular processes and disease pathways involving Septin 8. Its reliable performance and consistent results make it an ideal choice for studies in cell biology, cancer research, and beyond.
Product Name:
Septin 8 Monoclonal Antibody
SKU:
CAB21148
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-100 of human Septin 8 (NP_001287728.1).
This gene is a member of the septin family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse, and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
23176
Clone Number:
ARC2988
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using Septin 8 Rabbit mAb (CAB21148) at1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
