The Septin 4 Polyclonal Antibody (CAB10238) is a valuable tool for researchers studying Septin 4, a protein involved in cell division and cytoskeletal organization. This antibody, generated in rabbits, exhibits high specificity and sensitivity when detecting Septin 4 in human samples, making it suitable for various experimental applications such as Western blotting.Septin 4, a member of the septin family involved in cytokinesis and cellular morphogenesis, plays a crucial role in maintaining cell shape, motility, and polarity. Dysregulation of Septin 4 expression has been linked to various diseases, including cancer and neurological disorders, making it a promising target for further research and drug development.
By using the Septin 4 Polyclonal Antibody, researchers can investigate the function and regulation of Septin 4 in different cell types and disease contexts, providing valuable insights into its role in cellular processes and disease pathogenesis. This antibody is a valuable tool for advancing our understanding of Septin 4 biology and its potential implications for therapeutic interventions.
Product Name:
Septin 4 Rabbit Polyclonal Antibody
SKU:
CAB10238
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-100 of human Septin 4 (NP_536341.1).
This gene is a member of the septin family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse, and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. This gene is highly expressed in brain and heart. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. One of the isoforms (known as ARTS) is distinct; it is localized to the mitochondria, and has a role in apoptosis and cancer.
Purification Method:
Affinity purification
Gene ID:
5414
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using Septin 4 Rabbit pAb (CAB10238) at 1:500 dilution.Secondary antibody:HRP Goat Anti-Rabbit IgG (H+L)(CABS014) at 1:10000 dilution.Lysates / proteins: 25 μg per lane.Blocking buffer: 3 % nonfat dry milk in TBST.Detection:ECL Basic Kit (AbGn00020).Exposuretime: 5s.
