The Septin 11 Polyclonal Antibody (CAB12189) is a valuable tool for researchers studying the role of Septin 11 in cellular processes. Septin 11, a member of the septin family of GTP-binding proteins, is known to be involved in various cellular functions, including cell division, cell migration, and cytoskeletal organization.This polyclonal antibody, raised in rabbits, is highly specific and exhibits high reactivity with human samples. It has been validated for use in Western blot applications, allowing for the detection and analysis of Septin 11 protein levels in different cell types and tissues.Research involving Septin 11 is particularly relevant in the fields of cell biology, cancer research, and neurobiology, as dysregulation of septins has been associated with various diseases, including cancer and neurodegenerative disorders.
By studying the role of Septin 11 and its interactions with other proteins, researchers can gain valuable insights into the mechanisms underlying these diseases and potentially identify new therapeutic targets.Overall, the Septin 11 Polyclonal Antibody (CAB12189) is a reliable tool for researchers looking to enhance their understanding of Septin 11 biology and its implications in health and disease.
Product Name:
Septin 11 Rabbit Polyclonal Antibody
SKU:
CAB12189
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-120 of human Septin 11 (NP_060713.1).
SEPT11 belongs to the conserved septin family of filament-forming cytoskeletal GTPases that are involved in a variety of cellular functions including cytokinesis and vesicle trafficking (Hanai et al., 2004 [PubMed 15196925]; Nagata et al., 2004 [PubMed 15485874]).
Purification Method:
Affinity purification
Gene ID:
55752
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using Septin 11 Rabbit pAb (CAB12189) at 1:4000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
