The Septin 11 Polyclonal Antibody (CAB12040) is a valuable tool for researchers studying the role of Septin 11 in cellular functions and diseases. Septins are a family of GTP-binding proteins that play important roles in cell division, cytoskeletal organization, and membrane dynamics. This antibody, raised in rabbits, is highly specific to human Septin 11 and is validated for use in Western blot applications. It enables researchers to detect and analyze Septin 11 in various cell types, making it an ideal choice for studies in cell biology, cancer research, and neurobiology.Septin 11 has been implicated in various cellular processes, including cytokinesis, cell migration, and organelle segregation.
Dysregulation of Septin 11 has been linked to cancer progression, neurodegenerative diseases, and microbial infections. By studying the function of Septin 11 using this antibody, researchers can gain insight into the mechanisms underlying these diseases and potentially identify new therapeutic targets. Overall, the Septin 11 Polyclonal Antibody (CAB12040) is a valuable tool for researchers looking to delve into the complex functions of Septin 11 and its implications in health and disease.
Product Name:
Septin 11 Polyclonal Antibody
SKU:
CAB12040
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-120 of human Septin 11 (NP_060713.1).
SEPT11 belongs to the conserved septin family of filament-forming cytoskeletal GTPases that are involved in a variety of cellular functions including cytokinesis and vesicle trafficking (Hanai et al., 2004 [PubMed 15196925]; Nagata et al., 2004 [PubMed 15485874]).
Purification Method:
Affinity purification
Gene ID:
55752
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using Septin 11 Rabbit pAb (CAB12040) at 1:5000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
