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Septin 6 Polyclonal Antibody (CAB8196)

SKU:
CAB8196
Product Type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
€129 - €359
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:Septin 6 Polyclonal Antibody
SKU:CAB8196
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse,Rat
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 350-434 of human Septin 6 (NP_055944.2).
Sequence:VKEK EAEL KEAE KELH EKFD RLKK LHQD EKKK LEDK KKSL DDEV NAFK QRKT AAEL LQSQ GSQA GGSQ TLKR DKEK KNNP WLCT E
Tested Applications:WB ELISA
Recommended Dilution:WB,1:500 - 1:2000
Synonyms:SEP2; SEPT2; SEPT6; Septin 6
Positive Sample:Rat lung
Conjugate:Unconjugated
Cellular Localization:Chromosome, Cleavage furrow, Cytoplasm, Midbody, centromere, cytoskeleton, kinetochore, spindle.
Calculated MW:50kDa
Observed MW:50kDa

This gene is a member of the septin family of GTPases. Members of this family are required for cytokinesis. One version of pediatric acute myeloid leukemia is the result of a reciprocal translocation between chromosomes 11 and X, with the breakpoint associated with the genes encoding the mixed-lineage leukemia and septin 2 proteins. This gene encodes four transcript variants encoding three distinct isoforms. An additional transcript variant has been identified, but its biological validity has not been determined.

Purification Method:Affinity purification
Gene ID:23157
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Product ImageWestern blot analysis of extracts of Rat lung, using Septin 6 antibody (CAB8196) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.

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