The Sept6 Polyclonal Antibody (CAB8196) is a vital tool for researchers studying Sept6, a protein involved in cell division and cytokinesis. This rabbit-derived antibody is highly specific to human samples and has been validated for use in Western blot applications. By binding to the Sept6 protein, this antibody allows for accurate detection and analysis in a variety of cell types, making it an essential component for studies in cell biology and cancer research.Sept6, a member of the Septin family of GTP-binding proteins, plays a crucial role in promoting proper cell division and maintaining cellular structural integrity.
Dysregulation of Sept6 has been implicated in various diseases, including cancer and neurodegenerative disorders. By understanding the function and regulation of Sept6, researchers can gain valuable insights into disease mechanisms and potentially develop targeted therapies to combat these conditions.
Product Name:
Septin 6 Polyclonal Antibody
SKU:
CAB8196
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 350-434 of human Septin 6 (NP_055944.2).
This gene is a member of the septin family of GTPases. Members of this family are required for cytokinesis. One version of pediatric acute myeloid leukemia is the result of a reciprocal translocation between chromosomes 11 and X, with the breakpoint associated with the genes encoding the mixed-lineage leukemia and septin 2 proteins. This gene encodes four transcript variants encoding three distinct isoforms. An additional transcript variant has been identified, but its biological validity has not been determined.
Purification Method:
Affinity purification
Gene ID:
23157
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of Rat lung, using Septin 6 antibody (CAB8196) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
