The Sept3 Polyclonal Antibody (CAB16551) is a valuable tool for researchers studying Sept3, a member of the septin family of GTP-binding proteins involved in cytoskeletal organization and cell division. This antibody, generated in rabbits, exhibits high specificity for Sept3 in human samples and has been validated for Western blot applications. By detecting and quantifying Sept3 expression, researchers can gain insights into its role in cellular processes such as cytokinesis, cell migration, and vesicle trafficking.
Sept3 is implicated in various diseases, including cancer and neurodegenerative disorders, making it a promising target for therapeutic interventions. By elucidating the functions of Sept3 in these pathological contexts, researchers can potentially uncover novel treatment strategies. The Sept3 Polyclonal Antibody (CAB16551) offers a reliable tool for investigating the involvement of Sept3 in disease progression and may contribute to the development of targeted therapies in the future.
Product Name:
Septin 3 Rabbit Polyclonal Antibody
SKU:
CAB16551
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 179-358 of human Septin 3 (NP_663786.2).
This gene belongs to the septin family of GTPases. Members of this family are required for cytokinesis. Expression is upregulated by retinoic acid in a human teratocarcinoma cell line. The specific function of this gene has not been determined. Alternative splicing of this gene results in several transcript variants encoding different isoforms.
Purification Method:
Affinity purification
Gene ID:
55964
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using Septin 3 Rabbit pAb (CAB16551) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
