The Septin 2 Polyclonal Antibody (CAB5801) is a valuable tool for researchers studying Septin 2, a family of GTP-binding proteins that play essential roles in various cellular processes, including cytokinesis, membrane dynamics, and cell polarity. Raised in rabbits, this antibody is highly specific to human samples and is validated for use in Western blot applications.Septin 2 is known for its involvement in the formation of cellular structures such as the cytoskeleton and cell division machinery.
By targeting Septin 2, researchers can detect and analyze its expression levels in different cell types, providing insights into its functions and potential implications in diseases such as cancer and neurological disorders.This antibody offers researchers a reliable tool for investigating the role of Septin 2 in cellular processes and diseases, contributing to the advancement of knowledge in cell biology and potential therapeutic targets.
Product Name:
Septin 2 Rabbit Polyclonal Antibody
SKU:
CAB5801
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 112-361 of human Septin 2 (NP_004395.1).
Enables identical protein binding activity. Predicted to be involved in several processes, including cilium assembly; regulation of exocytosis; and smoothened signaling pathway. Predicted to act upstream of or within regulation of L-glutamate import across plasma membrane and regulation of protein localization. Located in several cellular components, including cytoskeleton; photoreceptor connecting cilium; and sperm annulus. Part of septin complex.
Purification Method:
Affinity purification
Gene ID:
4735
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using Septin 2 antibody (CAB5801) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
