The SEPSECS Polyclonal Antibody (CAB7103) is a valuable tool for researchers studying the SEPSECS protein, essential for selenocysteine synthesis. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding specifically to the SEPSECS protein, this antibody enables accurate detection and analysis in a variety of cell types, making it an excellent choice for studies in biochemistry and molecular biology.SEPSECS plays a crucial role in selenocysteine biosynthesis, a unique amino acid crucial for the activity of selenoproteins involved in antioxidant defense, redox regulation, and thyroid hormone metabolism.
Dysregulation of selenoprotein synthesis has been linked to various diseases, including cancer, cardiovascular disorders, and neurodegenerative conditions. Research into the function of SEPSECS is essential for understanding the molecular mechanisms underlying these diseases and developing targeted therapies. The SEPSECS Polyclonal Antibody is a valuable asset for scientists investigating selenocysteine metabolism and its implications in health and disease.
Product Name:
SEPSECS Rabbit Polyclonal Antibody
SKU:
CAB7103
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 222-501 of human SEPSECS (NP_058651.3).
The amino acid selenocysteine is the only amino acid that does not have its own tRNA synthetase. Instead, this amino acid is synthesized on its cognate tRNA in a three step process. The protein encoded by this gene catalyzes the third step in the process, the conversion of O-phosphoseryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec).
Purification Method:
Affinity purification
Gene ID:
51091
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using SEPSECS Antibody (CAB7103) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 3s.
