The SENP2 Polyclonal Antibody (CAB17994) is a valuable tool for researchers studying SENP2, a protein involved in post-translational modification and regulation of key cellular processes. This antibody, produced in rabbits, exhibits high specificity and sensitivity in detecting SENP2 in human samples, making it suitable for Western blot applications. By targeting SENP2, researchers can gain insights into its role in processes such as DNA repair, cell cycle regulation, and stress response.SENP2, a member of the sentrin/SUMO-specific protease family, plays a crucial role in the SENP-mediated deSUMOylation pathway, impacting the function of numerous proteins involved in various cellular functions.
Dysregulation of SENP2 has been linked to diseases such as cancer, neurodegenerative disorders, and cardiovascular diseases, making it a promising therapeutic target. By utilizing the SENP2 Polyclonal Antibody, researchers can deepen their understanding of SENP2's functions and potential implications for disease development, paving the way for innovative treatment strategies.
Product Name:
SENP2 Rabbit Polyclonal Antibody
SKU:
CAB17994
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 366-589 of human SENP2 (NP_067640.2).
cytosol, nuclear membrane, nuclear pore, nucleoplasm, nucleus, PML body
Calculated MW:
68kDa
Observed MW:
68kDa
SUMO1 (UBL1; MIM 601912) is a small ubiquitin-like protein that can be covalently conjugated to other proteins. SENP2 is one of a group of enzymes that process newly synthesized SUMO1 into the conjugatable form and catalyze the deconjugation of SUMO1-containing species.
Purification Method:
Affinity purification
Gene ID:
59343
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates, using SENP2 Rabbit pAb (CAB17994) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
