The SENP1 Rabbit Monoclonal Antibody (CAB4460) is a versatile tool for researchers studying SENP1, a crucial enzyme involved in regulating protein post-translational modifications. This antibody, generated in rabbits, exhibits high specificity and sensitivity when detecting SENP1 in various species, including human samples. Validated for use in Western blot applications, it allows for precise analysis of SENP1 expression levels in different cell types.SENP1, also known as sentrin-specific protease 1, plays a key role in controlling cellular processes such as DNA repair, cell cycle progression, and gene expression by mediating the deSUMOylation of target proteins. Dysfunction of SENP1 has been linked to various diseases, including cancer, neurodegenerative disorders, and cardiovascular conditions.
Research on SENP1 can provide insights into disease mechanisms and potential therapeutic strategies targeting this enzyme.By using the SENP1 Rabbit Monoclonal Antibody (CAB4460), scientists can further explore the functions of SENP1 and its impact on cellular pathways, offering new possibilities for advancing knowledge in the fields of molecular biology, oncology, and drug development. This antibody is a valuable tool for investigating the role of SENP1 in disease progression and may lead to the development of targeted treatments for various medical conditions.
Product Name:
SENP1 Rabbit Monoclonal Antibody
SKU:
CAB4460
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 400-501 of human SENP1 (Q9P0U3).
This gene encodes a cysteine protease that specifically targets members of the small ubiquitin-like modifier (SUMO) protein family. This protease regulates SUMO pathways by deconjugating sumoylated proteins. This protease also functions to process the precursor SUMO proteins into their mature form. Alternate splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
29843
Clone Number:
ARC1016
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using SENP1 Rabbit mAb (CAB4460) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
