The Semenogelin-1 Polyclonal Antibody (CAB5487) is a valuable tool for researchers studying Semenogelin-1, a major protein found in semen that plays a crucial role in sperm function and fertility. This antibody, produced through rabbit immunization, has been rigorously tested for specificity and sensitivity in a variety of research applications, including Western blot and immunohistochemistry.Semenogelin-1 is essential for sperm protection and motility, making it a key player in male reproductive health. By targeting Semenogelin-1 with this antibody, researchers can explore its function in fertility, reproductive disorders, and potential therapeutic interventions.
The high reactivity of this antibody with human samples ensures accurate and reliable results, making it an indispensable tool for studies in reproductive biology and assisted reproductive technologies.Overall, the Semenogelin-1 Polyclonal Antibody is a valuable resource for scientists investigating the intricate mechanisms of male fertility and reproductive health. Its reliability and specificity make it an essential component in advancing our understanding of Semenogelin-1 biology and its potential implications for human fertility and reproductive medicine.
Product Name:
SEMG1 Rabbit Polyclonal Antibody
SKU:
CAB5487
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 24-310 of human SEMG1 (NP_002998.1).
The protein encoded by this gene is the predominant protein in semen. The encoded secreted protein is involved in the formation of a gel matrix that encases ejaculated spermatozoa. This preproprotein is proteolytically processed by the prostate-specific antigen (PSA) protease to generate multiple peptide products that exhibit distinct functions. One of these peptides, SgI-29, is an antimicrobial peptide with antibacterial activity. This proteolysis process also breaks down the gel matrix and allows the spermatozoa to move more freely. This gene and another similar semenogelin gene are present in a gene cluster on chromosome 20.
Purification Method:
Affinity purification
Gene ID:
6406
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using SEMG1 antibody (CAB5487) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
