The Semaphorin 4C Polyclonal Antibody (CAB8225) is a specialized tool for researchers studying Semaphorin 4C, a protein belonging to the semaphorin family known for its role in axon guidance and immune regulation. This antibody, produced in rabbits, exhibits high specificity and reactivity with human samples, making it an essential tool for Western blot applications and immunohistochemistry studies.Semaphorin 4C is involved in various biological processes, including cell migration, angiogenesis, and immune response modulation. Its aberrant expression has been linked to diseases such as cancer, autoimmune disorders, and neurological conditions.
The Semaphorin 4C Polyclonal Antibody enables precise detection and analysis of Semaphorin 4C in a wide range of cell types, providing insights into its function and potential therapeutic implications.By using the Semaphorin 4C Polyclonal Antibody in their research, scientists can deepen their understanding of Semaphorin 4C's involvement in health and disease, paving the way for the development of targeted therapies and diagnostic tools. Invest in this antibody to unlock the mysteries of Semaphorin 4C and advance scientific knowledge in the fields of oncology, immunology, and neurology.
Product Name:
SEMA4C Rabbit Polyclonal Antibody
SKU:
CAB8225
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 749-833 of human SEMA4C (NP_060259.4).
Sequence:
HARC QPGG GPPS PPPG IPGQ PLPS PTRL HLGG GRNS NANG YVRL QLGG EDRG GLGH PLPE LADE LRRK LQQR QPLP DSNP EESS V
Tested Applications:
WBELISA
Recommended Dilution:
WB,1:500 - 1:2000
Synonyms:
SEMAF; SEMAI; SEMACL1; M-SEMA-F; SEMA4C
Positive Sample:
MCF7,BT-474,Mouse heart
Conjugate:
Unconjugated
Cellular Localization:
Cell junction, Cytoplasmic vesicle, Single-pass type I membrane protein, postsynaptic cell membrane, postsynaptic density, secretory vesicle, synapse, synaptic vesicle membrane.
Calculated MW:
93kDa
Observed MW:
110kDa
Predicted to enable chemorepellent activity and semaphorin receptor binding activity. Involved in muscle cell differentiation and positive regulation of stress-activated MAPK cascade. Located in extracellular space.
Purification Method:
Affinity purification
Gene ID:
54910
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using SEMA4C Rabbit pAb (CAB8225) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
