The Semaphorin 7A Polyclonal Antibody (CAB12039) is a valuable tool for researchers interested in studying Semaphorin 7A, a protein involved in cell-cell signaling and immune regulation. This antibody, produced in rabbits, has high reactivity with human samples and is validated for use in Western blot applications. By binding to Semaphorin 7A, this antibody enables researchers to detect and analyze this protein in various cell types, making it ideal for studies in immunology and cancer research.Semaphorin 7A is known for its role in immune regulation, specifically in modulating immune responses.
This makes it a key target for research into diseases such as cancer, autoimmune disorders, and chronic inflammatory conditions. Understanding the function of Semaphorin 7A is crucial for developing new therapies that target or manipulate immune responses in these disease contexts.Overall, the Semaphorin 7A Polyclonal Antibody (CAB12039) is a valuable tool for researchers interested in studying the role of Semaphorin 7A in immune regulation and disease, providing insights that may lead to potential therapeutic interventions in the future.
Product Name:
SEMA7A Rabbit Polyclonal Antibody
SKU:
CAB12039
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 45-280 of human SEMA7A (NP_003603.1).
This gene encodes a member of the semaphorin family of proteins. The encoded preproprotein is proteolytically processed to generate the mature glycosylphosphatidylinositol (GPI)-anchored membrane glycoprotein. The encoded protein is found on activated lymphocytes and erythrocytes and may be involved in immunomodulatory and neuronal processes. The encoded protein carries the John Milton Hagen (JMH) blood group antigens. Mutations in this gene may be associated with reduced bone mineral density (BMD). Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.
Purification Method:
Affinity purification
Gene ID:
8482
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using SEMA7A Rabbit pAb (CAB12039) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
