The SEMA4G Polyclonal Antibody (CAB15492) is a vital tool for researchers studying SEMA4G, a cell surface protein involved in various physiological processes, including cell adhesion and migration. This antibody, produced in rabbits, exhibits high specificity and sensitivity towards human samples, making it suitable for use in Western blot applications.SEMA4G is a member of the semaphorin protein family, known for its role in axon guidance and immune response regulation. Studies have shown that SEMA4G plays a crucial role in cancer progression, making it a potential therapeutic target for cancer treatment.
By using the SEMA4G Polyclonal Antibody, researchers can detect and analyze SEMA4G expression in different cell types, providing valuable insights into its function in cancer biology and other disease states.With its ability to target SEMA4G, this polyclonal antibody is a valuable tool for researchers interested in understanding the molecular mechanisms underlying cancer and other related diseases. Its high reactivity and specificity make it a reliable choice for immunology and cancer research studies.
Product Name:
SEMA4G Rabbit Polyclonal Antibody
SKU:
CAB15492
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 470-560 of human SEMA4G (NP_001190173.1).
Cell membrane, Single-pass type I membrane protein.
Calculated MW:
91kDa
Observed MW:
105kDa
Semaphorins are a large family of conserved secreted and membrane associated proteins which possess a semaphorin (Sema) domain and a PSI domain (found in plexins, semaphorins and integrins) in the N-terminal extracellular portion. Based on sequence and structural similarities, semaphorins are put into eight classes: invertebrates contain classes 1 and 2, viruses have class V, and vertebrates contain classes 3-7. Semaphorins serve as axon guidance ligands via multimeric receptor complexes, some (if not all) containing plexin proteins. Multiple transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
57715
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using SEMA4G Rabbit pAb (CAB15492) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5s.
