CD62P/P-selectin Rabbit Polyclonal Antibody (CAB1425)
- SKU:
- CAB1425
- Product Type:
- Antibody
- Reactivity:
- Human
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
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Description
Product Name: | CD62P/P-selectin Rabbit Polyclonal Antibody |
SKU: | CAB1425 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 30-200 of human CD62P/P-selectin (NP_002996.2). |
Sequence: | ISEL TNQK EVAA WTYH YSTK AYSW NISR KYCQ NRYT DLVA IQNK NEID YLNK VLPY YSSY YWIG IRKN NKTW TWVG TKKA LTNE AENW ADNE PNNK RNNE DCVE IYIK SPSA PGKW NDEH CLKK KHAL CYTA SCQD MSCS KQGE CLET IGNY TCSC YPGF YGPE CEYV REC |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:200 |
Synonyms: | CD62; GRMP; PSEL; CD62P; GMP140; LECAM3; PADGEM; CD62P/P-selectin |
Positive Sample: | Jurkat,LO2,Rat liver,Rat brain |
Conjugate: | Unconjugated |
Cellular Localization: | Membrane, Single-pass type I membrane protein. |
Calculated MW: | 91kDa |
Observed MW: | 115kDa |
This gene encodes a 140 kDa protein that is stored in the alpha-granules of platelets and Weibel-Palade bodies of endothelial cells. This protein redistributes to the plasma membrane during platelet activation and degranulation and mediates the interaction of activated endothelial cells or platelets with leukocytes. The membrane protein is a calcium-dependent receptor that binds to sialylated forms of Lewis blood group carbohydrate antigens on neutrophils and monocytes. Alternative splice variants may occur but are not well documented.
Purification Method: | Affinity purification |
Gene ID: | 6403 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |